Untersuchung der subzellulären Lokalisation der Rezeptortyrosinkinase HER-3

factor receptor 2, HER-2. Therefore to counterpart this overexpression of HER-2, a therapeutic monoclonal humanized antibody (Herceptin®) directed against the extracellular domain of HER-2 was developed [...] Additionally, breast cancer patients have a significant association between HER-2 expression and overall survival. Interestingly, 43.2 % of breast cancer patients showed a nuclear distribution of HER-3 with little [...] partner of HER-3 (HER-2) and the ligand (HRGb1). Both factors were investigated to determine if they influence the subcellular distribution of HER-3. A Doxycycline-inducible HER-2 overexpressing cell line …

Entwicklung eines in vitro Systems zur Untersuchung von substanzinduzierten Genexpressionsänderungen

Gsta5, Gsta2, Hsf1, Nqo1, Apex1, Bax, Cdkn1a, Gadd45a, Mt1a, Sds, Mdm2, Myc) and one gene group which is active during cell proliferation (gene group 2: Mcm6, Cdc2, Hdc, 3-Pgdh, Cdc20, Igfbp1, Top2a, Map3k1 [...] measuring additional genes (Bax, Cdkn1, Gsta2, Hsf1, Mdm2 und Nqo1). A concentration dependent effect could also be shown for aflatoxin B1, piperonylbutoxide and 2-nitrofluorene as additional liver-carcinogens [...] the classical collagen monolayer culture, where hepatocytes are cultured on a thin film of collagen, (2) the collagen sandwich culture, where hepatocytes are cultivated between two layers of a collagen gel …

Programmierung 2 | [[https://matrix.to/#/#tudo-dap2:fachschaften.org|#tudo-dap2]] | ^ Mathe für Informatik 1 | [[https://matrix.to/#/#tudo-mafi1:fachschaften.org|#tudo-mafi1]] | ^ Mathe für Informatik 2 | [[ht [...] to/#/#tudo-hoema:fachschaften.org|#tudo-hoema]] | ^ Höhere Mathematik 2 | [[https://matrix.to/#/#tudo-hoema2:fachschaften.org|#tudo-hoema2]] | ^ Höhere Mathematik 3 | [[https://matrix.to/#/#tudo-hoema3:fa [...] -statistik1:fachschaften.org|#tudo-statistik1]] | ^ Statistik 2 | [[https://matrix.to/#/#tudo-statistik2:fachschaften.org|#tudo-statistik2]] | ^ Steuerungs- und Reglungstechnik | [[https://matrix.to/# …

Exact Text Search and Ranked Retrieval – Lecture Notes

NEAR operator – usually 2–4× larger index) For TF-IDF, we can store the quantity/positions along with the document: bird → Doc 1 ×1, Doc 2 ×1 early → Doc 2 ×1, Doc 4 ×2 early → Doc 2 @ 4, Doc 4 @ 1,5 Ranked [...] Doc 1 1 1 1 1 1 1 Doc 2 1 1 1 1 1 1 1 1 Doc 3 1 1 1 1 1 1 Doc 4 1 1 1 1 1 1 1 1 1 1 1 intersection of bird AND early = 0011 AND 1010 = 0010 matching document: bit 2 = document 2. Exact Text Search – Inverted [...] document collections. Solution: We store only the 1’s, for each term , sorted. bird → Doc 1 , Doc 2 early → Doc 2 , Doc 4 Optimizations: sort lists, and use a merge operation to intersect lists in \(O(n+m)\) …

Exact Text Search and Ranked Retrieval – Lecture Notes

NEAR operator – usually 2–4× larger index) For TF-IDF, we can store the quantity/positions along with the document: bird → Doc 1 ×1, Doc 2 ×1 early → Doc 2 ×1, Doc 4 ×2 early → Doc 2 @ 4, Doc 4 @ 1,5 Ranked [...] Doc 1 1 1 1 1 1 1 Doc 2 1 1 1 1 1 1 1 1 Doc 3 1 1 1 1 1 1 Doc 4 1 1 1 1 1 1 1 1 1 1 1 intersection of bird AND early = 0011 AND 1010 = 0010 matching document: bit 2 = document 2. Exact Text Search – Inverted [...] document collections. Solution: We store only the 1’s, for each term , sorted. bird → Doc 1 , Doc 2 early → Doc 2 , Doc 4 Optimizations: sort lists, and use a merge operation to intersect lists in \(O(n+m)\) …

Microsoft Word - TR 08004 Stand 2008-05-27-Final.doc

getroffen und die Kosten im Netz gesenkt werden können. A1 An A3 A2 B D2 Dm D3 D1 C A1 A3 An A2 B C D2 D1 D3 Dn Seite 16 SFB 559 Abbildung 2: Systematische Darstellung des Ausschnittes eines typischen Lu [...] io Bündelungsszenario Maßnahme m= 1 2 3 4 Kurzbeschreibung Bündelungsgrad 10% Bündelungsgrad 30% Bündelungsgrad 50% Bündelungsgrad 60% Verursacher v(m) A2 A2 A2 A2 Ebene Akteur Kategorie Partialebene Standort [...] x unterscheidet sich von der des Gefangenendilemmas, siehe Tabelle 2. Koop. B Defkt. B Koop. A 3; 3 2; 4 Defkt. A 4; 2 1; 1 Tabelle 2: Beispiel Chicken Game Die Defektionsangst ist nicht mehr dominant …

Bier Chips EinkaufsID 0 1 1 1 1 1 0 2 0 1 1 3 1 0 0 4 {Aftershave} → {Bier} s = 1 4 , conf = 1 2 {Aftershave} → {Chips} s = 0 {Bier} → {Chips} s = 1 2 , conf = 2 3 (zusammen anbieten?) {Chips} → {Aftershave} [...] 3 {} f : 4 c : 3 a : 3 m : 2 p : 2 b : 1 m : 1 b : 1 c : 1 b : 1 p : 1 Item conditional pattern base c f : 3 a fc : 3 b fca : 1, f : 1, c : 1 m fca : 2, fcab : 1 p fcam : 2, cb : 1 Katharina Morik, Claus [...] conf1 l1 = {i1, · · · , ik−1, ik} c2 = {i1, · · · } → {ik−1, ik} conf2 · · · · · · · · · l1 = {i1, · · · , ik−1, ik} ck = {i1} → {· · · , ik−1, ik} confk conf1 ≥ conf2 ≥ · · · ≥ confk Katharina Morik, Claus …

Vorlesung Wissensentdeckung - Apriori

Bier Chips EinkaufsID 0 1 1 1 1 1 0 2 0 1 1 3 1 0 0 4 {Aftershave} → {Bier} s = 1 4 , conf = 1 2 {Aftershave} → {Chips} s = 0 {Bier} → {Chips} s = 1 2 , conf = 2 3 (zusammen anbieten?) {Chips} → {Aftershave} [...] 3 {} f : 4 c : 3 a : 3 m : 2 p : 2 b : 1 m : 1 b : 1 c : 1 b : 1 p : 1 Item conditional pattern base c f : 3 a fc : 3 b fca : 1, f : 1, c : 1 m fca : 2, fcab : 1 p fcam : 2, cb : 1 Katharina Morik, Claus [...] conf1 l1 = {i1, · · · , ik−1, ik} c2 = {i1, · · · } → {ik−1, ik} conf2 · · · · · · · · · l1 = {i1, · · · , ik−1, ik} ck = {i1} → {· · · , ik−1, ik} confk conf1 ≥ conf2 ≥ · · · ≥ confk Katharina Morik, Claus …

KOMDAT21-5vp.vp

Tagesgruppe 7.743 7.876 +1,7 8,5 8,6 ISE 2.016 1.793 -11,1 2,2 2,0 Fremdunterbringung 38.754 37.413 -3,5 42,8 40,7 Vollzeitpflege 10.087 10.302 +2,1 11,1 11,2 Heimerz., betreut. Wohnf. 28.667 27.111 -5,4 [...] -12 -10 -8 -6 -4 -2 0 2 4 6 8 unter 3 J. 3 < 6 J. 6 < 9 J. 9 < 12 J. 12 < 15 J. 15 < 18 J. 18 < 21 J. Altersgruppen -1,0 (3.564) -2,6 (5.259) -2,6 (5.259) -4,6 (12.121) -3,0 (16.765) +2,9 (23.469) -10,4 [...] 423 +5,0 57,2 59,3 Soziale Gruppenarbeit 8.488 8.890 +4,7 9,4 9,7 Erziehungsbeistandschaft. 11.210 11.998 +7,0 12,4 13,1 Betreuungshilfen 5.558 5.653 +1,7 6,1 6,2 SPFH1 16.838 18.213 +8,2 18,6 19,8 Tagesgruppe …