To content
Department of Statistics
Doctoral student

M.Sc. Julia Duda


TU Dort­mund Uni­ver­sity
Department of Sta­tis­tics
Statistical Methods in Genetics and Chemometrics
Mathematics Building, Room 916
44221 Dortmund

E-Mail: dudastatistik.tu-dortmundde
Phone: +49 231 755 6814

Portrait photo of Julia Duda © Julia Duda​/​private
  • since February 2020: Doctoral Student
  • 2013-2019: Study of Sta­tis­tics with minor in Biostatistics at TU Dort­mund Uni­ver­sity
    Master Thesis: Model Selection and Model Averaging of Dose-Response Gene Expression Data with MCP-Mod
  • 2017-2018: Year abroad at Michigan Technological University, Michigan, USA
  • Toxicology
  • Dose-Response Modeling




Ghallab, A., González Leiva, D. F., Strängberg, E., Hofmann, U., Myllys, M., Hassan, R., Hobloss, Z., Brackhagen, L., Begher-Tibbe, B., Duda, J. C., Drenda, C., Kappenberg, F., Reinders, J., Friebel, A., Vucur, M., Turajski, M., Seddek, A., Abbas, T., Abdelmageed, N., … Hengstler, J. G. (2024). Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis. Journal of Hepatology, 80(2), 268–281.

Tug, T., Duda, J. C., Menssen, M., Bruce, S. W., Bringezu, F., Dammann, M., Frötschl, R., Harm, V., Ickstadt, K., Igl, B.-W., Jarzombek, M., Kellner, R., Lott, J., Pfuhler, S., Plappert-Helbig, U., Rahnenführer, J., Schulz, M., Vaas, L., Vasquez, M., … Ziemann, C. (2024). In vivo alkaline comet assay: statistical considerations on historical negative and positive control data. Regulatory Toxicology and Pharmacology, Article 105583. In press.


Duda, J. C., Drenda, C., Kästel, H., Rahnenführer, J., Kappenberg, F. (2023). Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons. Scientific Reports [ISSN: 2045-2322], 13(1).

Kappenberg, F., Duda, J. C., Schürmeyer, L., Gül, O., Brecklinghaus, T., Hengstler, J. G., Schorning, K., & Rahnenführer, J. (2023). Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review. Archives of Toxicology. In press.

Su, H., Haque, M., Becker, S., Edlund, K., Duda, J. C., Wang, Q., Reißing, J., Marschall, H., Candels, L. S., Mohamed, M., Sjöland, W., Liao, L., Drexler, S. A., Strowig, T., Rahnenführer, J., Hengstler, J. G., Hatting, M., & Trautwein, C. (2023). Long‐term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals. Liver International. In press.


Brecklinghaus, T., Albrecht, W., Duda, J. C., Kappenberg, F., Gründler, L., Edlund, K., Marchan, R., Ghallab, A., Cadenas, C., Rieck, A., Vartak, N., Tolosa, L., Castell, J. V., Gardner, I., Halilbasic, E., Trauner, M., Ullrich, A., Zeigerer, A., Demirci Turgunbayer, Ö., … , Hengstler, J. G. (2022). In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay. Toxicology Letters, 368, 33–46.

Brecklinghaus, T., Albrecht, W., Kappenberg, F., Duda, J. C., Vartak, N., Edlund, K., Marchan, R., Ghallab, A., Cadenas, C., Günther, G., Leist, M., Zhang, M., Gardner, I., Reinders, J., Russel, F. GM., Foster, A. J., Williams, D. P., Damle-Vartak, A., Grandits, M., … , Hengstler, J. G. (2022). The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds. Chemico-Biological Interactions, 351, Article 109728.

Brecklinghaus, T., Albrecht, W., Kappenberg, F., Duda, J. C., Zhang, M., Gardner, I., Marchan, R., Ghallab, A., Turgunbayer, Ö. D., Rahnenführer, J., & Hengstler, J. G. (2022). Influence of bile acids on the cytotoxicity of chemicals in cultivated human hepatocytes. Toxicology in Vitro, 81, Article 105344.

Duda, J. C., Hengstler, J. G., & Rahnenführer, J. (2022). td2pLL: an intuitive time-dose-response model for cytotoxicity data with varying exposure durations. Computational Toxicology, 43, Article 100234.

Duda, J. C., Kappenberg, F., & Rahnenführer, J. (2022). Model selection characteristics when using MCP‐Mod for dose–response gene expression data. Biometrical Journal, 64(5), 883–897.


Ghallab, A., Myllys, M., Friebel, A., Duda, J. C., Edlund, K., Halibasic, E., Vucur, M., Hobloss, Z., Brackhagen, L., Begher-Tibbe, B., Hassan, R., Burke, M., Genç, E., Frohwein, L. J., Hofmann, U., Holland, C. H., González Leiva, D. F., Keller, M., Seddek, A., … , Hengstler, J. G. (2021). Spatio-temporal multiscale analysis of Western diet-fed mice reveals a translationally relevant sequence of events during NAFLD progression [OnlineRessource]. Cells, 10(10), Article 2516.


  • Organization of Data Science in Context (WiSe 2020/2021)